Lung Cancer Mortality of Workers Exposed to Hexavalent Chromium
- Challenge: Cardno ChemRisk was asked by several chromate manufacturers to address concerns about a potential link between hexavalent chromium and lung cancer.
- Approach: Cardno ChemRisk scientists conducted a retrospective epidemiology study of workers to determine lung cancer mortality rates and dose-response modeling using nearly 30 years of industrial hygiene data and employment records for more than 1,000 workers.
- Findings: The study reported an increased risk of lung cancer mortality associated with hexavalent chromium exposure, and the results were used to calculate the dose-response curve and cancer potency factors.
- Value: The Occupational Safety and Health Administration (OSHA) used the results as part of their assessment of the occupational exposure standard.