Lung Cancer Mortality of Workers Exposed to Chromium (VI)
This project involved a retrospective epidemiology study of workers to determine lung cancer mortality rates and dose-response modeling to determine the increased risk of lung cancer from exposure to hexavalent chromium. Cardno ChemRisk scientists evaluated nearly 30 years of industrial hygiene data and employment records for more than 1,000 workers for the Painesville, Ohio, workers (so-called Diamond Shamrock Cohort). The results of the research were used by the Occupational Safety and Health Administration (OSHA) during their re-evaluation of the dose-response curve and cancer potency factors for airborne hexavalent chromium, and were published in the peer-reviewed literature (see Crump et al. 2003; Proctor et al. 2003, Proctor et al.2004).