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Centers of Excellence

Posted by on in Centers of Excellence

Posted on behalf of author Fian Louie

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Posted by on in Centers of Excellence

Senior Health Scientist Denise Hill, PhD, was appointed to the Board of Directors of the Product Stewardship Society® (PSS) at its annual meeting, Stewardship 2016, held in Baltimore, Maryland, May 23-25.  Affiliated with the American Industrial Hygiene Association, PSS is an independent professional society dedicated to promoting responsible design, development, and management of products throughout their life cycle.

PSS provides resources, professional development, and networking opportunities to individuals who have a role in product stewardship and sustainability inside and outside of the business sector.  Its members comprise a broad range of disciplines, from environmental health and safety (EHS) professionals, toxicologists, and industrial hygienists to sustainability and product steward specialists.

In accepting her two-year appointment, Dr. Hill welcomed the opportunity to contribute to the profession and the continued growth of the PSS and meet the newly emerging challenges of product stewardship with the global community of stewardship professionals.

Dr. Hill, an expert in human health toxicology, is the applied toxicology service area lead for Cardno ChemRisk.  She has more than 12 years of professional experience, including extensive expertise in inborn errors of metabolism, nutrient metabolism, gene-environment interactions, and exposure to environmental contaminants and pharmaceuticals as they relate to birth defects.  Her research in neurodevelopmental toxicology investigated the molecular mechanisms that give rise to defects in the developing nervous system.  She received her doctoral degree in toxicology from Texas A&M University.

For more information contact:

Denise Hill, PhD
Senior Health Scientist
Phone: + 1 713-722-5326

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Posted by on in Centers of Excellence
The Environmental Protection Agency has published a new lifetime Health Advisory for  Perfluorooctanoic Acid (PFOA) and Perfluorooctane Sulfonate (PFOS) found in drinking water. The EPA concluded that 0.07 ppb is an adequate Health Advisory level "not expected to result in adverse health effects over a lifetime exposure." Find out more about the new Health Advisory level from the EPA here and from a Cardno ChemRisk scientist here.
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Posted by on in Centers of Excellence

There has been a proliferation of tools and approaches designed to help stakeholders, such as product manufacturers, certify how "green" their chemicals and products are. These tools/approaches can also help in the earlier stages of product design, when choosing among alternatives. However, with a large number of choices in the marketplace, understanding the assumptions and outputs of these tools/approaches is necessary for correct implementation. In an earlier effort, we assessed and scored 32 tools, discovering that there is an emphasis on hazard evaluation among them.

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Posted by on in Centers of Excellence
Pierce et al. published “An updated evaluation of reported no-observed adverse effect levels for chrysotile asbestos for lung cancer and mesothelioma” in the online version of the Critical Reviews in Toxicology journal last month. This article is an update to the review article published in 2008 titled “An evaluation of reported no-effect chrysotile asbestos exposures for lung cancer and mesothelioma.”

The general findings of the updated study are:

·         Based on our review of 16 eligible groups of chrysotile-exposed workers, we determined a best-estimate NOAEL range for lung cancer of 89-168 fibers/cc-years and for pleural mesothelioma of 208-415 fibers/cc-years. 

·         None of the studies of workers exposed to medium and short (grade 4 – 7) chrysotile reported an increased risk of either disease at any exposure level.  This supports that medium and short fiber chrysotile, which was used in hundreds of products (e.g., automotive brakes, and clutches, gaskets, roofing products, joint compound, etc.) may have no carcinogenic potential.

·         Of the seven cases of peritoneal mesothelioma reported in all studies combined, none were observed in the analyses of medium and short chrysotile-exposed workers in the absence of crocidolite exposure.

The abstract of the article is available here.

Please contact Jennifer Pierce for more information.
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