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Posted by on in Centers of Excellence
The Environmental Protection Agency has published a new lifetime Health Advisory for  Perfluorooctanoic Acid (PFOA) and Perfluorooctane Sulfonate (PFOS) found in drinking water. The EPA concluded that 0.07 ppb is an adequate Health Advisory level "not expected to result in adverse health effects over a lifetime exposure." Find out more about the new Health Advisory level from the EPA here and from a Cardno ChemRisk scientist here.
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Posted by on in Policy/Regulatory Support

Posted on behalf of Angela Perez

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Posted by on in Centers of Excellence

There has been a proliferation of tools and approaches designed to help stakeholders, such as product manufacturers, certify how "green" their chemicals and products are. These tools/approaches can also help in the earlier stages of product design, when choosing among alternatives. However, with a large number of choices in the marketplace, understanding the assumptions and outputs of these tools/approaches is necessary for correct implementation. In an earlier effort, we assessed and scored 32 tools, discovering that there is an emphasis on hazard evaluation among them.

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Posted by on in Centers of Excellence
Pierce et al. published “An updated evaluation of reported no-observed adverse effect levels for chrysotile asbestos for lung cancer and mesothelioma” in the online version of the Critical Reviews in Toxicology journal last month. This article is an update to the review article published in 2008 titled “An evaluation of reported no-effect chrysotile asbestos exposures for lung cancer and mesothelioma.”

The general findings of the updated study are:

·         Based on our review of 16 eligible groups of chrysotile-exposed workers, we determined a best-estimate NOAEL range for lung cancer of 89-168 fibers/cc-years and for pleural mesothelioma of 208-415 fibers/cc-years. 

·         None of the studies of workers exposed to medium and short (grade 4 – 7) chrysotile reported an increased risk of either disease at any exposure level.  This supports that medium and short fiber chrysotile, which was used in hundreds of products (e.g., automotive brakes, and clutches, gaskets, roofing products, joint compound, etc.) may have no carcinogenic potential.

·         Of the seven cases of peritoneal mesothelioma reported in all studies combined, none were observed in the analyses of medium and short chrysotile-exposed workers in the absence of crocidolite exposure.

The abstract of the article is available here.

Please contact Jennifer Pierce for more information.
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Posted by on in Centers of Excellence

Brooke Tvermoes, Ph.D., will be speaking at the GMA Science Forum – Connecting Sound Science with Sound Policy, to be held April 18-21, 2016, at the Capital Hilton in Washington, D.C. The GMA, or Grocery Manufacturers Association, is a trade association "representing the makers of the world's favorite food, beverage and consumer products" and assisting their members with diverse issues such as to "spur economic growth; ensure access to safe, healthy, and affordable foods; market [their] products responsibly; and tackle hunger relief." For the past decade, the GMA Science Forum has kept scientists and decision makers in the industry informed. This year's Forum will "provide attendees with multiple views and actions to be taken in order to ensure policies, laws and regulations are based on sound, up-to-date science, and achieve compliance with the ever changing regulatory environment."  

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The Cardno ChemRisk View

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Cardno ChemRisk is a respected scientific consulting firm headquartered in San Francisco with locations and consultants across the U.S. While our website provides a formal look at our capabilities, the Cardno ChemRisk View provides an informal voice too. Various Cardno ChemRisk consultants will be sharing news and views about current trends, happenings and methodologies in the industry. We’ll also highlight activities of interest at Cardno ChemRisk, within confidentiality restrictions of course.

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